The defining feature of modern Bugatti since the introduction of the Veyron in 2005 has been the W16 engine. That engine is no more. However, fortunately for the still-to-be-named Chiron replacement, Bugatti will retain 16 cylinders but now in a vee formation with added hybridization. Beyond announcing the cylinder count and layout, Bugatti remains tight-lipped on further details but has provided an audio snippet of the new powertrain.
Read about some of the more notable 16-cylinder engines through the ages here.